MELODY

Methods for Localization of Different Types of breast lesions (PI: Helle Skjerven)

Study Population. Female and male patients with invasive breast cancer or DCIS scheduled for breast-conserving surgery with an imaging-guided localization.

Inclusion Criteria:

• Signed informed consent form
• Malignant breast lesion requiring breast-conserving surgery and imaging-guided localization (either DCIS or invasive breast cancer; multiple or bilateral lesions and the use of neoadjuvant chemotherapy are allowed)
• Planned surgical removal of the lesion using one or more of the following imaging-guided localization techniques:
  • Wire-guided localization
  • Intraoperative ultrasound
  • Magnetic localization
  • Radioactive seed localization
  • Radioguided Occult Lesion Localization (ROLL)
  • Radar localization
  • Radiofrequency identification (RFID) tag localization
  • Ink/carbon localization
• Female / male patients ≥ 18 years old

Exclusion Criteria:

• Patients not suitable for surgical treatment
• Patients requiring mastectomy as first surgery
• Surgical removal without imaging-guided localization